TGFβ promotes low IL10-producing ILC2 with profibrotic ability involved in skin fibrosis in systemic sclerosisPaôline Laurent, Benoit Allard, Pauline Manicki, Valérie Jolivel, Emeline Levionnois, Mohamed Jeljeli, Pauline Henrot, Julien Izotte, Damien Leleu, Alexis Groppi, Julien Seneschal, Joel Constans, Carlo Chizzolini, Christophe Richez, Pierre DuffauSee the full list of authors
20 July 2021
Molecular basis for clinical diversity between autoantibody subsets in diffuse cutaneous systemic sclerosisKristina Elizabeth Neergaard Clark, Corrado Campochiaro, Eszter Csomor, Adam Taylor, Katherine Nevin, Nicholas Galwey, Mary A Morse, Jennifer Singh, Yee Voan Teo, Voon H Ong, Emma Derrett-Smith, Nicolas Wisniacki, Shaun M Flint, Christopher P Denton
6 July 2021
Single-cell transcriptome analysis identifies skin-specific T-cell responses in systemic sclerosisAlyxzandria M Gaydosik, Tracy Tabib, Robyn Domsic, Dinesh Khanna, Robert Lafyatis, Patrizia Fuschiotti
24 May 2021
Comprehensive analysis of the major histocompatibility complex in systemic sclerosis identifies differential HLA associations by clinical and serological subtypesMarialbert Acosta-Herrera, Martin Kerick, Elena Lopéz-Isac, Shervin Assassi, Lorenzo Beretta, Carmen Pilar Simeón-Aznar, Norberto Ortego-Centeno, International SSc Group, Susanna M Proudman, Australian Scleroderma Interest Group (ASIG), Nicolas Hunzelmann, Gianluca Moroncini, Jeska K de Vries-Bouwstra, Gisela Orozco, Anne BartonSee the full list of authors
1 April 2021
X-linked inhibitor of apoptosis protein (XIAP) inhibition in systemic sclerosis (SSc)Christina Bergmann, Ludwig Hallenberger, Sara Chenguiti Fakhouri, Benita Merlevede, Amelie Brandt, Clara Dees, Honglin Zhu, Ariella Zehender, Xiang Zhou, Annemarie Schwab, Chih-Wei Chen, Andrea Hermina Györfi, Alexandru Emil Matei, Debomita Chakraborty, Thuong Trinh-MinhSee the full list of authors
26 April 2021
Targeting human plasmacytoid dendritic cells through BDCA2 prevents skin inflammation and fibrosis in a novel xenotransplant mouse model of sclerodermaRebecca L Ross, Clarissa Corinaldesi, Gemma Migneco, Ian M Carr, Agne Antanaviciute, Christopher W Wasson, Antonio Carriero, Jörg H W Distler, Steve Holmes, Yasser M El-Sherbiny, Clive S McKimmie, Francesco Del Galdo
4 February 2021
Autoantibodies targeting telomere-associated proteins in systemic sclerosisBrittany L Adler, Francesco Boin, Paul J Wolters, Clifton O Bingham, Ami A Shah, Carol Greider, Livia Casciola-Rosen, Antony Rosen
25 January 2021
Anti-centromere antibodies target centromere–kinetochore macrocomplex: a comprehensive autoantigen profilingNobuhiko Kajio, Masaru Takeshita, Katsuya Suzuki, Yukari Kaneda, Humitsugu Yamane, Kazuhiro Ikeura, Hidekazu Sato, Shin Kato, Hiroyuki Shimizu, Kazuyuki Tsunoda, Tsutomu Takeuchi
18 November 2020
New composite endpoint in early diffuse cutaneous systemic sclerosis: revisiting the provisional American College of Rheumatology Composite Response Index in Systemic SclerosisDinesh Khanna, Suiyuan Huang, Celia J F Lin, Cathie Spino
30 November 2020
Machine learning integration of scleroderma histology and gene expression identifies fibroblast polarisation as a hallmark of clinical severity and improvementKimberly Showalter, Robert Spiera, Cynthia Magro, Phaedra Agius, Viktor Martyanov, Jennifer M Franks, Roshan Sharma, Heather Geiger, Tammara A Wood, Yaxia Zhang, Caryn R Hale, Jackie Finik, Michael L Whitfield, Dana E Orange, Jessica K Gordon
7 October 2020