Pharmacodynamics of the S1P receptor modulator cenerimod in a phase 2b randomised clinical trial in patients with moderate to severe SLEMadeleine Suffiotti, Pijus Brazauskas, Marcel Peter Keller, Ouali Berkani, Gustavo Seifer, Peter Cornelisse, Mark Joseph Murphy, Daniel Stefan Strasser
24 November 2024
Evaluation and prediction of relapse risk in stable systemic lupus erythematosus patients after glucocorticoid withdrawal (PRESS): an open-label, multicentre, non-inferiority, randomised controlled study in ChinaYunyun Fei, Lidan Zhao, Lijun Wu, Xiaoxia Zuo, Rongli Li, Jiaomei Cheng, Hui Luo, Xue Wu, Li Sun, Jingjing Xu, Yingxuan Zhu, Yang Wang, Zhu Chen, Xiaomei Li, Xiaofei WangSee the full list of authors
13 November 2024
Molecular basis for the disease-modifying effects of belimumab in systemic lupus erythematosus and molecular predictors of early response: blood transcriptome analysis implicates the innate immunity and DNA damage response pathwaysGeorgia-Savina Moysidou, Panagiotis Garantziotis, George Sentis, Dimitra Nikoleri, Nikolaos Malissovas, Myrto Nikoloudaki, Eirini-Maria Stergioti, Styliani Polia, Nikolaos Paschalidis, Anastasia Filia, Maria Grigoriou, Dionysis Nikolopoulos, Noemin Kapsala, Spyridon Katechis, Antonis FanouriakisSee the full list of authors
7 November 2024
Management of systemic lupus erythematosus: a systematic literature review informing the 2023 update of the EULAR recommendationsMyrto Kostopoulou, Chetan B Mukhtyar, George Bertsias, Dimitrios T Boumpas, Antonis Fanouriakis
22 May 2024
Single-cell transcriptomics reveal potent extrafollicular B cell response linked with granzyme K CD8 T cell activation in lupus kidneyChunmei Wu, Shan Jiang, Zechuan Chen, Teng Li, Xixi Gu, Min Dai, Fang Du, Yan Ye, Longhai Tang, Mingyuan Wang, Xiaodong Wang, Ting Li, Shuang Ye, Chunde Bao, Xiaoming ZhangSee the full list of authors
17 October 2024
BCMA-CD19 compound CAR T cells for systemic lupus erythematosus: a phase 1 open-label clinical trialWeijia Wang, Shanzhi He, Wenli Zhang, Hongyu Zhang, Vincent M DeStefano, Masayuki Wada, Kevin Pinz, Greg Deener, Darshi Shah, Nabil Hagag, Min Wang, Ming Hong, Ronghao Zeng, Ting Lan, Yu MaSee the full list of authors
22 May 2024
Remission and low disease activity are associated with lower healthcare costs: results from the Systemic Lupus International Collaborating Clinics (SLICC) inception cohortMegan R W Barber, Manuel Francisco Ugarte-Gil, John G Hanly, Murray B Urowitz, Yvan St-Pierre, Caroline Gordon, Sang-Cheol Bae, Juanita Romero-Diaz, Jorge Sanchez-Guerrero, Sasha Bernatsky, Daniel J Wallace, David A Isenberg, Anisur Rahman, Joan T Merrill, Paul R FortinSee the full list of authors
16 May 2024
Haematopoietic stem cell-derived immune cells have reduced X chromosome inactivation skewing in systemic lupus erythematosusAmy L Roberts, Alessandro Morea, Ariella Amar, Magdalena West, Sarah Karrar, Rhiannon Lehane, Philip Tombleson, Deborah Cunningham Grahman, John A Reynolds, Chloe C Y Wong, David L Morris, Kerrin S Small, Timothy J Vyse
27 June 2024
Blood RNA-sequencing across the continuum of ANA-positive autoimmunity reveals insights into initiating immunopathologyLucy Marie Carter, Md Yuzaiful Md Yusof, Zoe Wigston, Darren Plant, Stephanie Wenlock, Adewonuola Alase, Antonios Psarras, Edward M Vital
13 May 2024
Characterisation of choroid plexus-infiltrating T cells reveals novel therapeutic targets in murine neuropsychiatric lupusErica Moore, Sushma Bharrhan, Deepak A Rao, Fernando Macian, Chaim Putterman
26 March 2024